Tuesday, June 4, 2019

Can Botulinum Lethal Toxin Turned to be Beneficial Substance?

Illustration

I'm still excited about botulinum toxin, since I know that botulinum toxin is a potent and deadly substance.

This substance produced by a kind of a rod bacteria that can exist in low or free oxygen, Clostridium botulinum.

Even though this kind of bacteria are very common in sample of water and soil throughout the world, the canned foods and honey also can be contaminated.

It was many years ago, especially in the under developing countries, This toxin was a killer that hard to overcome. Clostridium botulinum release toxin that able to kill human.

The early of symptoms of this toxin are fatigue, weak, blur eyes, and vertigo. 

Following by difficult to swallow and speak, also vomiting and diarrhea or constipation.

Then it can radiant to weakness in the neck and arms, and muscle in lower body.

This toxin can cause seizure and dead because it impacts nervous system. It can cause flaccid paralysis that leads to respiratory failure, because diaphragm muscle, and muscle related to breathing process becomes weak and paralyze.

As we know botulinum toxic have been identified as:
- Foodborne botulism. It occurs by consuming food that contaminate with this kind of bacteria or their spore. The spore can germinate and produce toxin too.

- Wound botulism. It could be caused by the wound infection. The open wound infected by the spores or bacteria.

- Infant botulism. The baby ingest the spore and then in the baby's gut bacteria grow and release toxin. It infect the baby under 6 months.

- Inhalation botulism, when the person inhaled the botulinum concentrate (aerosolized), It intents to biology weapon or bioterrorism.


Why does the toxin lethal and deadly? The toxin can cause the paralysis of peripheral neuromuscular junction, which is the junction between our nerve to the muscle.

The muscle or striated muscle will excited whenever the nerve release chemical substance acetylcholine.

Botulinum then inactive the protein that regulate release of acetylcholine. Because acetylcholine releasing is prevented by toxin, the muscle cannot excite anymore and becomes paralyze.

Good news that engineers turned this lethal toxin to beneficial substance. The purified protein of botulinum toxin when administered by injection into the muscle, it can cause local paralyze.

Based on the concepts, this toxin is used in pharmacology for certain disorders, and also for specifically anti-wrinkle.

Now, I understand that botulinum toxin can be used to cure and heal some diseases beside for cosmetic such as face rejuvenation.

68 comments:

  1. Very interesting article Evi. Thank you very much for making it understandable. In the sutras there is the teaching that nature (also human) has the power to transform the poisonous substance into medicine. You have left me thinking, friend.

    Big hug and thanks again.

    ReplyDelete
    Replies
    1. Appreciate
      Can Botulinum Lethal Toxin Turned to be Beneficial Substance?
      -
      I'm still excited about botulinum toxin, since I know that botulinum toxin is a potent and deadly substance.

      Delete
  2. Very interesting post!! Have a nice day

    ReplyDelete
    Replies
    1. Appreciate
      Can Botulinum Lethal Toxin Turned to be Beneficial Substance?
      -
      This substance produced by a kind of a rod bacteria that can exist in low or free oxygen, Clostridium botulinum.

      Delete
  3. Interesante lo que compartes y desconocía. Un gusto leerte. Saludos

    ReplyDelete
    Replies
    1. Can Botulinum Lethal Toxin Turned to be Beneficial Substance?
      -
      Even though this kind of bacteria are very common in sample of water and soil throughout the world, the canned foods and honey also can be contaminated.

      Delete
  4. Replies
    1. Appreciate
      Can Botulinum Lethal Toxin Turned to be Beneficial Substance?
      -
      It was many years ago, especially in the under developing countries, This toxin was a killer that hard to overcome. Clostridium botulinum release toxin that able to kill human.

      Delete
  5. Very interesting, now I understand more about it ^^
    xx

    ReplyDelete
    Replies
    1. Appreciate
      Can Botulinum Lethal Toxin Turned to be Beneficial Substance?
      -
      The early of symptoms of this toxin are fatigue, weak, blur eyes, and vertigo.

      Delete
  6. Replies
    1. Thank you
      -
      Following by difficult to swallow and speak, also vomiting and diarrhea or constipation.

      Delete
  7. You have amazing knowledge

    ReplyDelete
    Replies
    1. Thank you Joanna
      -
      This substance produced by a kind of a rod bacteria that can exist in low or free oxygen, Clostridium botulinum.

      Delete
  8. I have never heard about it, have a lovely day☺

    ReplyDelete
  9. Interesting substance. That is fantastic that there is a way it can be used as a benefit.

    ReplyDelete
  10. Hello ✿!
    What a most interesting post.
    I did not know this information and I found it very curious.
    A huge kiss ❄

    ReplyDelete
  11. So many important information here in this post - I follow you too xx

    ReplyDelete
  12. Thank you for sharing! It was interesting to learn that this toxic substance can be turned to a beneficial substance!
    xx from Bavaria/Germany, Rena
    www.dressedwithsoul.com

    ReplyDelete
  13. Great post.
    www.rsrue.blogspot.com

    ReplyDelete
  14. Interesting post my dear, thank you for sharing :-)

    ReplyDelete
  15. Thanks for the interesting post (:

    ReplyDelete
  16. I have no idea that this toxin can be so deadly.

    ReplyDelete
  17. Muy interesante te mando un beso

    ReplyDelete
  18. Was realy interesting to read. 😊👍🏼

    ReplyDelete
  19. Tu blog es una enciclopedia,te felicito

    ReplyDelete
  20. Thats new to me. One thing bad turned in one thing good. Great, thanks for sharing it.
    Xoxo

    marisasclosetblog.com

    ReplyDelete
  21. Knowledge makes all the difference in our life! Have a great day.

    Blog Paisagem de Janela
    www.paisagemdejanela.com

    ReplyDelete
  22. É preciso conhecer pois só o conhecimento pode nos mostrar os dois lados de uma mesma substância
    Beijinhos

    ReplyDelete
  23. This was so interesting!! I didn't know that about botulinum toxin!! Have a great day!! Big hugs :)

    Lisa
    A Mermaid's Crafts

    ReplyDelete
  24. Zainteresował mnie tytuł, czytając tekst cały czas zastanawiałam się jak toksyn która powoduje takie dolegliwości, może działać pozytywnie. A tu proszę nawet silna trucizna, może być stosowana do leczenia, no i do usuwania zmarszczek :)

    ReplyDelete
  25. Niesamowite, coś co truje można z korzyścią wykorzystać,aby leczyło! Pozdrawiam serdecznie

    ReplyDelete
  26. What an interesting post, your blog is amazing! will keep on following you, thank you for visiting mine!

    ReplyDelete
    Replies
    1. Thank you Diana
      -
      Botulinum then inactive the protein that regulate release of acetylcholine. Because acetylcholine releasing is prevented by toxin, the muscle cannot excite anymore and becomes paralyze.

      Delete
  27. Kompletnie się na tym nie znam, dzięki Tobie wciąż dowiaduję się wielu ciekawych rzeczy.
    Serdecznie pozdrawiam :)

    ReplyDelete
  28. Interesting post! I learn with.
    Kiss

    ReplyDelete
  29. Interesante , y te dire nena yo prefiero en lo posible las cosas artesanales, naturales libres de preservantes, no me gusta lo enlatado!!

    Besos y feliz semana!!😄😄

    ReplyDelete
  30. what an interesting post~ easy to understand :)
    I was studying Biology too in University
    We're in the same frequency haha

    ReplyDelete
  31. another alternative instead of botox?

    ReplyDelete
    Replies
    1. Many.
      Thank you Anies
      -
      Botulinum then inactive the protein that regulate release of acetylcholine. Because acetylcholine releasing is prevented by toxin, the muscle cannot excite anymore and becomes paralyze.

      Delete
  32. Another interesting post! Thank you for sharing interesting information!
    Greetings from hot Poland!

    ReplyDelete
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