The
cartoon above is an illustration about a relationship of Brain and
Heart that I pulled from the awkwardyetidotcom.
In
previous posts, several signs of the early onset Alzheimer's dementia
had been covered. Now, it is about the late onset, the symptoms
appear when a person in the mid 60s and later of age.
The
exactly causes of late onset are remaining unknown. The scientists
believe the cause could be a combination of three factors:
-
life style
-
environment
-
genetic.
Genetic
markers related to the late onset form of Alzheimer's disease is
associated with chromosome 19.
The
mutation genes that cause increase Apoliprotein E (APOE). A person
who inherit one copy of the APOE e4 has a big chance for developing
this disease.
APOE
primarily produced by liver and macrophages, and APOE4 is associated
with hyperlipidaemia and hypercholesterolemia.
Generally,
the APOE is associated with various conditions of disease
progression, not only Alzheimer's Disease, but also:
-
Multiple Sclerosis
-
Parkinson's Disease
-
Vascular Dementia
-
Type 2 Diabetes Melitus
-
Ischemia Stroke
-
Type III Hyperlipoproteinemia.
Astrocyte
(Neuroscience, Purves et al).
In
our brain, APOE is mainly produced by astrocyte
In
the late onset Alzheimer's disease, there are three type APOEs:
-
APOE2 is associated with reduced risk of Alzheimer's
-
APOE3 the most common variant and is considered neutral
-
APOE4 is associated with a greater risk.
The
function of APOE is to regulate lipid transport from one cell type or
tissue to another.
In
our brain, APOE is mainly produced by astrocyte and its function is
to transport cholesterol to our nerve cell (neuron) in the brain.
Whenever
an imbalance between the production and clearance of beta-amyloid
peptide in our brain, thus, the accumulation and aggregation of
beta-amyloid will be occurred. This become a toxic in our brain.
This
toxicity also depend on the paired helical filaments of the
microtubuli-associated protein tau.
So, in the late onset Alzheimer's disease, the toxic in the brain
destroy the nice balancing of healthy brain, prominently the two
proteins which are called beta-amyloid and tau.
Very interesting. Thanks for the information.
ReplyDeleteBest regards
i am ERIC BRUNT by name. Greetings to every one that is reading this testimony. I have been rejected by my wife after three(3) years of marriage just because another Man had a spell on her and she left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address AKHERETEMPLE@gmail.com have help a woman to get back her husband and i gave him a reply to his address and he told me that a man had a spell on my wife and he told me that he will help me and after 3 days that i will have my wife back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my wife. Thanks for helping me Dr Akhere contact him on email: AKHERETEMPLE@gmail.com
Deleteor
call/whatsapp:+2349057261346
i am ERIC BRUNT by name. Greetings to every one that is reading this testimony. I have been rejected by my wife after three(3) years of marriage just because another Man had a spell on her and she left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address AKHERETEMPLE@gmail.com have help a woman to get back her husband and i gave him a reply to his address and he told me that a man had a spell on my wife and he told me that he will help me and after 3 days that i will have my wife back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my wife. Thanks for helping me Dr Akhere contact him on email: AKHERETEMPLE@gmail.com
or
call/whatsapp:+2349057261346
Appreciate..
DeleteWhat are Factors Causing the Late Onset Alzheimer's Diseases?- Alzheimer’s 07
-
The cartoon above is an illustration about a relationship of Brain and Heart that I pulled from the awkwardyetidotcom.
Eric> Appreciate:
DeleteWhat are Factors Causing the Late Onset Alzheimer's Diseases?- Alzheimer’s 07
-
In previous posts, several signs of the early onset Alzheimer's dementia had been covered. Now, it is about the late onset, the symptoms appear when a person in the mid 60s and later of age.
Interesting information.
ReplyDeleteAppreciate:
DeleteWhat are Factors Causing the Late Onset Alzheimer's Diseases?- Alzheimer’s 07
-
The exactly causes of late onset are remaining unknown. The scientists believe the cause could be a combination of three factors:
- life style
- environment
- genetic.
I wonder if my doctor is willing to check my APOE gene. Thanks for sharing, Evi.
ReplyDeleteAppreciate:
DeleteWhat are Factors Causing the Late Onset Alzheimer's Diseases?- Alzheimer’s 07
-
Genetic markers related to the late onset form of Alzheimer's disease is associated with chromosome 19.
Such great points to consider! Thanks for sharing.
ReplyDeletewww.jessicabroyles.com
Appreciate:
DeleteWhat are Factors Causing the Late Onset Alzheimer's Diseases?- Alzheimer’s 07
-
The mutation genes that cause increase Apoliprotein E (APOE). A person who inherit one copy of the APOE e4 has a big chance for developing this disease.
It is a terrible disease! May our Lord gives all of us good health.
ReplyDeleteVery good information Thank you!
ReplyDeleteThose kind of post are always very interesting!
ReplyDeleteFull of very important informations!
Thanx for share!
XO
S
https://s-fashion-avenue.blogspot.com
INteresting! Thanks for sharing
ReplyDeletethank you so much for this post :)
ReplyDeleteGreat contribution you are getting spread with this series about Alzheimer's, Evi. Humor and not so much. I would say wisdom to be able to express it and make it clear and that it remains even sharper.
ReplyDeleteHuge hug!!
Sharper is correct? Means very clear?
ReplyDeleteThanks for sharing, it is in my family.
ReplyDeleteInteresting post
ReplyDeleteGreat post!
ReplyDeletewww.somosvisiveiseinfinitos.com.br
Hi Evi what an interesting post ,thankyou for sharing your information with us xx
ReplyDeleteSo great post
ReplyDeleteKisses
www.pimentadeacucar.com
Gracias por la información. Uno debe cuidarse del Alzheimer como las otras enfermedades Te mando un beso
ReplyDeleteI think a check of the APOE gene check really would make sense ...
ReplyDeletexx from Bavaria/Germany, Rena
www.dressedwithsoul.com
Thank you for spreading the awareness about Alzheimer's.
ReplyDeletehttps://sarahrizaga.blogspot.com/
Thanks for the info, thats a terrible deasese.
ReplyDeleteXoxo
marisasclosetblog.com
thanks for sharing :D
ReplyDeleteGenetik pastinya faktor utama ya
ReplyDeleteIt's a terrible disease. Thanks for the information.
ReplyDeleteBuena información para los que tenemos una edad avanzada
ReplyDeleteInteresting information :)
ReplyDeleteI must confes i´ve learned a lot about the Alzheimer's thanks to you
ReplyDeleteInteresante información. Tengo un familiar con esa enfermedad. Saludos y abrazo amiga.
ReplyDeleteThanks a lot :D
ReplyDeletevery interesting post
NEW MAN TO MAN POST | MODERN MEN TAKE CARE OF THE HAIR!
Instagram ∫ Facebook Official Page ∫ Miguel Gouveia / Blog Pieces Of Me :D
Good to know more about this disease.
ReplyDeleteGood post with an important topic
ReplyDeleteInteresting entry.
ReplyDeleteVert interesting! Have a lovely weekend ☺
ReplyDeleteThank you & have a sunny day :).
ReplyDeleteThat cartoon is pretty funny:D And thank you for another informative post about Alzheimer.
ReplyDeleteMudah2an nanti aku udah tuanya gak alzheimer. Waktu itu pernah nonton film apa ya lupa... tentang alzheimer itu. Aku jadi ngeri :(
ReplyDeleteThanks for sharing :)
ReplyDeletegracias por la información.
ReplyDeleteUn beso! ;)
Very useful info ❤
ReplyDeleteÓtimo post!
ReplyDeletebjs
http://www.pinkbelezura.com/
Celebo te sigan gustando mis fotos.
ReplyDeleteSaludos desde Andalucia
(。◕ ‿ ◕。)/ Holaaa!!!
ReplyDeleteJustamente el otro día vi en la televisión que estaban haciendo estudios para detectar esta enfermedad desde la juventud, si fuera así se supone que encontrarían una posible solución. Gracias por la información :D
Te invito a visitar mi humilde espacio ♥
穛 S4Ku SEK4i®
very helpful post:)
ReplyDeleteinteresting information
ReplyDeleteI've always wondered where Alzheimer comes from?
greetings
Lili
Absolutely delicious =)
ReplyDeleteVery interesting, thanks for the information.
So if someone has already got a specific disease written above, and his father or mother passed away caused by alzheimer's, he is vulnerable to inherit this illness?
ReplyDeletethat's a terrible disease hope they find a cure.
ReplyDeletexoxo
marisasclosetblog.com
Its a terrible disease :(
ReplyDeleteCreo que se está avanzando mucho la investigación sobre la enfermedad y que se están probando nuevos fármacos para combatirla.
ReplyDeleteBesos
Alzheimer's is really scary and debilitating. Thanks for sharing.
ReplyDeleteGracias por este artículo Evi. Me ha parecido muy interesante. Muchísimas gracias, el alzheimer es una enfermedad muy, muy importante.
ReplyDeleteBesos :D
Belum ada artikel baru nih
ReplyDeleteTo bardzo skomplikowane, mam nadzieję że mnie ominie ta okropna choroba. Serdeczności Evi.
ReplyDeleteThanks for sharing, it was interesting post.
ReplyDeletenice pictuures
ReplyDeleteVery interesting information, thank you!
ReplyDeletexx
These posts are really interesting and I've been bookmarking them, hoping I won't ever need to refer to them, yet knowing it's always a possibility.
ReplyDeleteUm post muito útil! Confesso que já estava a par de alguma desta informação, pois é um tema pelo qual me interesso, até porque tenho uma pessoa amiga, que há alguns anos atrás foi diagnosticada com esta doença!...
ReplyDeleteBeijinho
Ana
i believe, life style and environment contribute more not only for Alzheimer but also for other diseases
ReplyDeleteThanks for sharing, it was interesting post.Kisses
ReplyDeletei am ERIC BRUNT by name. Greetings to every one that is reading this testimony. I have been rejected by my wife after three(3) years of marriage just because another Man had a spell on her and she left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address AKHERETEMPLE@gmail.com have help a woman to get back her husband and i gave him a reply to his address and he told me that a man had a spell on my wife and he told me that he will help me and after 3 days that i will have my wife back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my wife. Thanks for helping me Dr Akhere contact him on email: AKHERETEMPLE@gmail.com
ReplyDeleteor
call/whatsapp:+2349057261346
i am ERIC BRUNT by name. Greetings to every one that is reading this testimony. I have been rejected by my wife after three(3) years of marriage just because another Man had a spell on her and she left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address AKHERETEMPLE@gmail.com have help a woman to get back her husband and i gave him a reply to his address and he told me that a man had a spell on my wife and he told me that he will help me and after 3 days that i will have my wife back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my wife. Thanks for helping me Dr Akhere contact him on email: AKHERETEMPLE@gmail.com
or
call/whatsapp:+2349057261346