Monday, August 26, 2019

Why does Gum Disease cause Alzheimer's Disease?- Alzheimer's 08

Porphyromonas gingivalis, bacteria cause the gum disease.

Tau or neurofibrillary tangles protein is one of landmarks of the Alzheimer's disease. It is abnormal accumulation of protein in the brain cells.

The abnormal conditions of Tau spread from one neuron to another neuron. Their patterns are exactly the same with the spreading of infections.

The researchers, Stephen Dominy and his colleagues, reported that toxic enzymes from the bacteria Porphyromonas gingivalis were found about 99 and 96 percent of 54 human Alzheimer’s brain samples, that correlated with tau and ubiquitin pathology.

Porphyromonas gingivalis is Gram-negative anaerobic bacterium that produces virulence factor that we called gingipains, which is a protein-degrading enzyme. 


Gum infections (Credit: Shutterstock)

There is a wide range of bacteria in our mouth. Porphymonas gingivalis causes the gum disease. The big group of bacteria grow and forming a plaque, and the worse one they release toxins and cause inflammation.

Once the oral cavity is infected by P. gingivalis, they may access the brain through some pathway including cranial nerves, monocytes, endothelial cell in the blood brain barriers.

When P. gingivalis enter the brain, they spread slowly for years and also damage neuron to neuron.
Gum disease or gingivitis is common and preventable. Symptoms include swollen, red, and tender gums. Regular dentist visits are important for gum disease prevention and treatments.

Treatment includes professionally cleaning around teeth to prevent bone damage. Prevention can begin at home by brushing and flossing twice a day. 

86 comments:

  1. I didn't know this but I'm not surprised, given the reputation of gum disease as a major problem child in the body.

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  2. This is very interesting is studying
    Biochemistry at university of Minnesota She hopes to get her Dr and work in a lab and do reseach she is a senior this year. She does do in volunteer in a lab now. Now looking for a gad school
    Laura Quaglia

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  3. Thank you Miss Evi for this ifnormation really usefull for me

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  4. Good to know! I need to take more care of teeth!

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  5. Uy gracias por el consejo . Siempre es bueno cuidar de nuestra salud y de nuestra salud oral. Te mando un beso

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  6. Hi Evi oh boy i never realised this,quite frightening really,thankyou for letting us know xx

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  7. This motivates me even more to take care of my teeth!
    xx from Bavaria/Germany, Rena
    www.dressedwithsoul.com

    ReplyDelete
    Replies
    1. Indeed :)
      -
      The abnormal conditions of Tau spread from one neuron to another neuron. Their patterns are exactly the same with the spreading of infections

      Delete
  8. Thanks for the useful review! ­čĹŹ

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    Replies
    1. Thank you Inna
      -
      The researchers, Stephen Dominy and his colleagues, reported that toxic enzymes from the bacteria Porphyromonas gingivalis were found about 99 and 96 percent of 54 human Alzheimer’s brain samples, that correlated with tau and ubiquitin pathology.

      Delete
  9. Thanks for share!
    HAPPY WEEK
    xoxo
    https://stylishpatterns.blogspot.com

    ReplyDelete
    Replies
    1. Thank you
      -
      Once the oral cavity is infected by P. gingivalis, they may access the brain through some pathway including cranial nerves, monocytes, endothelial cell in the blood brain barriers.

      Delete
  10. Wow, I didn't know this. Now I'll look forward to my dentist appointment in a couple of weeks instead of dreading it!! Have a great day!! Big hugs :)

    Lisa
    A Mermaid's Crafts

    ReplyDelete
    Replies
    1. :)
      -
      Gum disease or gingivitis is common and preventable. Symptoms include swollen, red, and tender gums. Regular dentist visits are important for gum disease prevention and treatments.

      Delete
  11. I didn't know that Alzheimer's causes such problems
    greetings
    Lili

    ReplyDelete
    Replies
    1. Thank you
      -
      Tau or neurofibrillary tangles protein is one of landmarks of the Alzheimer's disease. It is abnormal accumulation of protein in the brain cells.

      Delete
  12. I didn't know about this- so big portion of knowledge in this post

    ReplyDelete
    Replies
    1. Thank you
      -
      The abnormal conditions of Tau spread from one neuron to another neuron. Their patterns are exactly the same with the spreading of infections.

      Delete
  13. Replies
    1. Thank you Pathy
      -
      Porphyromonas gingivalis is Gram-negative anaerobic bacterium that produces virulence factor that we called gingipains, which is a protein-degrading enzyme.

      Delete
  14. Another great article, Evi. The amount of forecasts and care we must take is incredible. Everything we must understand. Fortunately we have posts like yours.

    Hugs and more hugs.

    ReplyDelete
    Replies
    1. Thanks Carlos
      -
      There is a wide range of bacteria in our mouth. Porphymonas gingivalis causes the gum disease.

      Delete
  15. Nie wiedziałam o tym. To kolejny powód żeby dbać o zęby.
    Serdeczno┼Ťci Evi :)

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  16. Interesting post my dear, thank you for sharing.

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  17. Todo lo que nos ense├▒as es divino ! Me encantar├şa verte pronto por mi blog ! Que tengas un excelente d├şa ! ♡♡♡

    ReplyDelete
  18. Un post come sempre molto interessante, grazie per aver condiviso questa tua conoscenza.
    sinforosa

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  19. Tu blog es una gran fuente de informaci├│n

    ReplyDelete
  20. Replies
    1. It is
      -
      There is a wide range of bacteria in our mouth. Porphymonas gingivalis causes the gum disease.

      Delete
  21. What a coincidence you should post this now … I've just been to the dental hygienist today!
    It is important to look after our teeth and gums.

    All the best Jan

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  22. Bisa gitu ya? Bakteri dari mulut (gusi) menjalar ke otak dan menyebabkan penyakit yang berbeda. Thank you sharingnya :)

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  23. It is important to keep our gums healthy.

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  24. I heard about this, it's terrifying. Thanks for sharing!

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  25. Good to know! Thanks for sharing.

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  26. Really interesting post. Thanks for sharing.

    Kisses

    ReplyDelete
    Replies
    1. thank you
      -
      There is a wide range of bacteria in our mouth. Porphymonas gingivalis causes the gum disease.

      Delete
  27. Not good bacteria not cool but requires treatment

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  28. Las ciencias avanzan,pero las enfermedades no le permiten descansar

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  29. Very interesting post.

    www.paginasempreto.blogspot.com.br

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  30. Very interesting post

    Kisses
    www.pimentadeacucar.com

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  31. Interesting post!

    https://www.biigthais.com/

    Kisses ;*

    ReplyDelete
    Replies
    1. Thank you
      -
      There is a wide range of bacteria in our mouth. Porphymonas gingivalis causes the gum disease.

      Delete
  32. so, moral of the story please take care of your health teeth...

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  33. Oh wow I didn´t know this fact about this disease
    xx

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  34. Que interesante, eso no lo sabia. Saludos amiga.

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  35. I had no idea! thanks for sharing!

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  36. Thank you for information. Have a sunny day.
    Nancy :)

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  37. Hello!
    Thank you for the information. Very interesting!

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  38. Como se ve, es muy importante la higiene dental. Suelo limpiarme los dientes con un cepillo el├ęctrico.

    Besos

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  39. I didn't know that gum infection can be so dangerous.

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  40. Muy interesante. Yo intento lavarmelos diariamente pero desde ahora pondre mucho más interes en ello. Un beso

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  41. Kak evi.. is it true Memory lost is one of Alzheimer sign? And gum infection I really worry read this :(

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  42. Muchas gracias, como siempre, por la valiosa informaci├│n.
    Un beso.

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  43. This comment has been removed by the author.

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  44. This comment has been removed by the author.

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  45. First time I know that! But I know that taking care of our Gum and tooth is so important, I had already worked as dental auxiliary, I know a lot of things except that.

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  46. Very interesting, i hadn't known before i read this article

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  47. En los paises del tercer mundo es donde están esos grandes contagios

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  48. This information help have an understanding keeping dental appointment and dental care is important

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  49. Alzeimer merupakan penyakit yang gejalanya tidak bisa di prediksi. Obatnya pun belum di temukan ya?
    Semoga kita semua terjauh dari penyakit.amiinn..

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  50. wow what an incredibly informative sharing dear Evi !!!!!!!!!!!!!!!!!!!

    you are doing such a great job by shring facts that may we never know normally

    THANK YOU SOOOOOOO MUCH!!!

    i had never a slightest idea or doubt or knowledge that dental care can be connected to brain itself

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  51. Thank you very much Evi for informing us of this interesting scientific study.
    I wish you a splendid Monday and good start of the month and week!
    A hug.

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  52. Very interresting informations. Thanks dear :)

    ReplyDelete

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